Neurium 600 inject, 5 pcs

Upute za korištenje Neurium 600 inject, 5 pcs

Important notes (compulsory information):

Neurium® 600 mg / 24 ml inject. Active ingredient: alpha-lipoic acid, ethylene bis (azan) salt. Areas of application: For disproportions for diabetic nerve damage (polyneuropathy).

For risks and side effects, read the package leaflet and ask your doctor or pharmacist!


Leaflet: Information for the User
Neurium 600 mg / 24 ml inject
Concentrate for the production of an infusion solution
Active ingredient: alpha-lipoic acid, ethylene bis (azan) salt

Read the entire leaflet carefully because it contains important information for you. This medicine is available without prescription. However, in order to achieve the best possible treatment success, neurium 600 mg / 24 ml inject must be applied in accordance with properly.

• Lift the package leaflet. You might want to read it again.
• Ask your pharmacist if you need more information or advice.
• If your symptoms get worse or no improvement occurs, you must definitely visit a doctor.
• If one of the listed side effects you significantly affect it or notice side effects that are not specified in this information information, please inform your doctor or pharmacist.

This leaflet contains:

1. What is neurium 600 mg / 24 ml inject and what is it used for?
2. What do you need to consider before using Neurium 600 mg / 24 ml inject?
3. How to use Neurium 600 mg / 24 ml inject?
4. WHAT SIDE EFFECTS ARE POSSIBLE?
5. How to keep neurium 600 mg / 24 ml inject?
6. ADDITIONAL INFORMATION

1. What is neurium 600 mg / 24 ml inject and what is it applied for?

Alpha-lipoic acid, the active ingredient in neurium 600 mg / 24 ml of inject, is a substance formed at higher living beings in the body's own metabolism, which influences certain material changing performance of the body. In addition, alpha-lipoic acid has the nerve cell from reactive degradation products protective (antioxidant) Properties.

Neurium 600 mg / 24 ml injekt is applied to disengagement in diabetic nerve damage (polyneuropathy).

2. What do you need to know before using Neurium 600 mg / 24 ml inject?

Neurium 600 mg / 24 ml inject must not be used,
If it is hypersensitive (allergic) to alpha-lipoic acid or any of the other ingredients of neurium 600 mg / 24 ml inject. Children and adolescents are to be excluded from treatment with neurium 600 mg / 24 ml injury, as there is no sufficient experience for this age group.

Take special care with Neurium 600 mg / 24 ml inject
In connection with the application of neurium 600 mg / 24 ml injury as injection or infusion solution, allergic reactions (Hypersensitivity reactions up to the life-threatening shock (sudden circular failure) observed (see section 4.4 side effects).

Therefore, your attending physician will become the occurrence of early symptoms during the use of neurium 600 mg / 24 ml injury (eg. As itching, nausea, malaise, etc.) monitor. If these occur, therapy must be stopped immediately; If necessary, further therapeutic measures are required. After application of neurium 600 Mg / 24 ml inject can be perceived a modified smell of the urine, which has no clinical relevance.

When using neurium 600 mg / 24 ml injury with other medicines
Please inform your doctor or pharmacist if you take / use other medicines or recently taken / applied, even if it is non-prescription medicines. It can not be ruled out that the simultaneous application of neurium 600 Mg / 24 ml injury leads to effect loss of cisplatin (a cancer agent.

The blood sugar-lowering effects of medicaments against diabetes (insulin or other medicines for sugar disease, which are taken) can be reinforcedbecome T. Therefore, in particular at the beginning of therapy with neurium 600 mg / 24 is ml injugal displays a tight blood sugar control. In individual cases, it may be necessary to avoid sub-sugar phenomena to reduce the insulin dose or the dose of the medicine against diabetes according to the instructions of the attending physician.

When using neurium 600 mg / 24 ml injected together with food and beverages
The regular treat of alcohol represents a significant risk factor for the emergence and progression of diseases associated with injuries of nerves, and thus can also take the success of treatment with neurium 600 mg / 24 affect ml inject. Therefore, patients with diabetic nerve damage (polyneuropathy) is generally recommended to avoid the enjoyment of alcohol as far as possible. This also applies to therapy intervals.

pregnancy and breast feeding period
Ask your doctor or pharmacist for advice before taking / application of all medicines.

It corresponds to the general principles of pharmacotherapy, during pregnancy and lactation of medicines only after careful benefit risk balancing. Pregnant and nursing ends should undergo treatment with alpha-lipoic acid only after careful recommendation and monitoring by the doctor, as so far no experiences with this patient group are available. Special studies on animals have not shown any indications of fertility disorders or fruit harmful effects. Nothing is known about a possible transfer of alpha-lipoic acid into the breast milk.

Verility and the use of machines
There are no special precautions required.

3. How to use Neurium 600 mg / 24 ml of inject?

Always use Neurium 600 mg / 24 ml inject exactly as directed in this leaflet.

Please ask your doctor or pharmacist if you are not sure.

Unless otherwise prescribed by the doctor, the usual dose is:
For strongly pronounced malpractices of diabetic polyneuropathy, the daily dosage is 1 ampoule neurium 600 mg / 24 ml inject (corresponding to 600 mg of alpha lipoic acid).

type of application
Neurium 600 mg / 24 ml injury is mixed with 250 ml of physiological saline and as a short term venot (Short infusion) applied (over at least 30 minutes). Because of the photosensitivity of the active ingredient, the short-infusion should be prepared shortly before the application. The infusion solution can be protected with aluminum foil against light. The light-protected infusion solution is stable for about 6 hours. It should be ensured that the minimum infusion time is adhered to 30 minutes.

Duration of the application
Neurium 600 mg / 24 ml inject is used over a period of 2-4 weeks in the initial phase of the treatment. In order to continue the treatment, 300 mg to 600 mg of alpha-lipoic acid should be taken daily in capsule, tablet or coated tablet form.

The basis of diabetic polyneuropathy therapy is the optimal diabetes setting. Please talk to your doctor or pharmacist if you have the impression that the effect of neurium 600 mg / 24 ml injury is too strong or too weak.

If you have used a larger amount of neurium 600 mg / 24 ml inject than you should
In overdose, nausea, vomiting and headaches may occur. In individual cases, when taking more than 10 g of alpha-lipoic acid, especially with simultaneous high alcohol consumption, severity, z. T. Observed life-threatening poisoning phenomena (such as generalized convulsions, derailment of the acid-Base budget with lactic acidosis, severe blood clotting disorders). Therefore, there is suspected a significant overdose with neurium 600 MG / 24 ml injury requires immediate clinic management and the initiation of measures under the general treatment principles of poisoning cases. If you have further questions about the application of the medicine, ask your doctor or pharmacist.

4. Which side effects are possible?

Like all medicines, this medicine can also have side effects, but they do not have to occur each other.

The frequency information on side effects is based on the following categories:
Very often:	more than 1 treated from 10
Frequently:	1 to 10 treated from 100
Occasionally:	1 to 10 treated from 1 000
Rarely:	1 to 10 treated from 10 000
Very rare:	less than 1 treated from 10 000
Not known:	Frequency on the basis of the available data does not estimate.

Gastrointestinal tract
Occasionally:
Nausea and vomiting

Reactions to the place of application
Very rare:
Reactions to the injection site

Hypersensitivity reactions
Allergic reactions like rash, hives (urticaria) and itching as well as hypersensitivity reactions of the whole body to shock can occur.

Nervous system
Occasionally:
Change or disturbance of the sense of taste
Very rare:
Spasmaps as well as double

Blood and blood vessels
Very rare:
Skin bleeding (purpura), disorders of platelet function and thus the blood clotting
(Thrombopeathies)
Body in total:
Frequently:
After rapid intravenous injection of headdress and breathing, which spontaneously decay.
Very rare:
Due to improved glucose utilization, blood sugar levels can fall. Complaints were described as with underto sugar with dizziness, sweating, headaches and vision disorders.

Countermeasures
If you are observing the above-mentioned side effects, neurium 600 mg / 24 ml inject should not be applied again. Notify your doctor so that it can decide on the severity and, if applicable, further measures.

In the first signs of a hypersensitivity reaction, the medicinal product must be set up and contacted immediately with a physician. Please inform your doctor or pharmacist if one of the listed side effects will significantly affect it or notice side effects that are not specified in this document formation.

5. How to keep neurium 600 mg / 24 ml inject?

Store drug out of reach of children.

You may not use the medicinal product after the expiration date specified on the label and the outer carton. The expiration date refers to the last day of the month.

Storage conditions:
Do not store over 25 ºC.
Keep the ampoules in the carton to protect the content from light.

Note on durability after breaking or preparation
Due to the photosensitivity of the active ingredient, the ampoules of the folding box should only be removed shortly before the application. The duration of durability after dilution with physiological saline solution is light-protected 6 hours.

6. Further information

What contains neurium 600 mg / 24 ml inject:
The active ingredient is alpha-lipoic acid, ethylene bis (azan) salt
Figure 24 with 24 ml infusion solution concentrate contains 775 mg of alpha-lipoic acid, ethylene bis (Azan) salt (corresponding to 600 mg of alpha lipoic acid).

The other ingredient is:
Water for injection purposes

Like neurium 600 mg / 24 ml of inject looks and content of the pack:
Packs of 5 and 10 ampoules with 24 ml each concentrate for the production of an infusion solution

Pharmaceutic entrepreneur
HEXAL AG
Industriestraße 25
83607 Holzkirchen
Telephone: (08024) 908-0
Fax: (08024) 908-1290
E-mail: [email protected]

Manufacturer
Salutas pharma GmbH,
A company of HEXAL AG
Otto-von-Guericke-Allee 1
39179 Bar life

This information information was last revised in December 2011.

Source: Information of the leaflet
Status: 08/2014