Bolfo Spot-on Fpronil 402 mg for very large dogs, 3 pcs

Upute za korištenje Bolfo Spot-on Fpronil 402 mg for very large dogs, 3 pcs

Important notes (compulsory information):

Bolfo Spot-on. Active substance: Fipronil. Areas of application: for the treatment of dogs against flea infestation (Ctenocephalides Felis). The veterinary medicinal product shows an immediate and up to 8 weeks-continuous insecticidal efficacy against newlyfight with adult fleas. The acaricidal effectiveness against IXodes Ricinus holds up to 2 weeks, against Rhipicephalus sanguineus up to 3 weeks and against Dermacentor reticulatus up to 4 weeks. If ticks of these species are present at the time of application, not all ticks are killed in the first 48 hours, but possibly only within a week.

For risks and side effects read the leaflet and ask your vet or pharmacist.



Bolfo Spot-on Fpronil Solution for Clicking For Dogs
Antiparasitic against fleas and ticks

Composition:
1 ml solution contains:
Active ingredients: 100 mg fipronil

Other ingredients:
Butylhydroxyanisol (ph.eur.) (E320), butylhydroxytoluene (ph.eur.) (E321), Povidone K12, polysorbate 80, butane-1-ol, diethylene glycol monoethyl ether (ph.eur.).

Dosage form:
Solution for dripping. Clear, colorless to pale yellow solution.

Target types:
dog

Application areas:
To treat dogs against flea infestation (Ctenocephalides Felis). The veterinary medicinal product shows an immediate and up to 8 weeks-continuous insecticidal efficacy against newlyfight with adult fleas.
The acaricidal effectiveness against IXodes Ricinus holds up to 2 Weeks, against Rhipicephalus sanguineus up to 3 weeks and against Dermacentor reticulatus up to 4 weeks. If ticks of these species are present at the time of application, not all ticks are killed in the first 48 hours, but possibly only within a week.

Contraindications:
Do not use in dogs with a body weight under 2 kg.
Do not apply at puppies in the age of 8 weeks, as there are no investigations.
Do not apply to sick (systemic disorders, fever, etc.) or convalescent animals. Do not apply to rabbits, as it can lead to side effects, under certain circumstances with death.
This veterinary medicinal product has been specially developed for dogs. Do not apply to cats, as this can lead to overdose.
Do not use with known hypersensitivity to the active ingredient or any of the other ingredients.

Special warnings for each target type:
This veterinary medicinal product does not prevent the ticks suck on the animals, but ticks may be in the first 24-48 hours after infestation and killed before full swelling, which reduces the risk of transmission of diseases. Tattered ticks often fall from the animal and remaining ticks can usually be easily removed by careful pulling out.
For optimal control of flea infestation in a household with several animals, all dogs and cats in this household should be treated with a suitable insecticide.
A suction of individual ticks is possible. Under unfavorable conditions, therefore, a transfer of infectious diseases can not be completely excluded. Fleas of pets often affect baskets, lying ceilings and usual resting sites such. B. Carpets and upholstered furniture, which should therefore be treated with a suitable insecticide and at the beginning of the control measure with a suitable insecticide and should be extracted regularly.
Frequent swimming or shampooing of the animal must be avoided as the conservation of the efficacy of the veterinary medicinal product was not investigated under these conditions.

Special precautions for the application:
(i) Special precautions for use in animals
Avoid contact with the eyes of the animal. If the veterinary medicinal product accidentally gets into the eyes to safely rinse them with water carefully.
Only for external use. Before the treatment, the animals are exactly weighing. It is important to ensure that the veterinary medicinal product is applied at a location that the animal can not lick the patch, and ensure that treated animals can not be mutually ill. Do not apply the veterinary medicinal product to wounds or skin lesions.

(ii) Special precautions for the user
This veterinary medicinal product can cause irritation of the mucous membrane and the eyes. Therefore, the contact of the veterinary medicinal product is to be avoided with her mouth and eyes.
After accidental contact with the eye, rinse this immediately carefully with water. When the eye irritation persists, consult a doctor and show the leaflet or label.

Persons with known hypersensitivity to Fipronil or the adjuvants (see section Composition) should avoid contact with the veterinary medicinal product.
Avoid contact with your fingers. If this happens, wash hands with water and soap. Wash hands after use. During treatment, neither drink, eat nor smoking. Treated animals should not be touched and children should not play with treated animals before the application site is dry. Therefore, the animals are not recommended during the day, but in the early evening hours. Freshly treated animals should not be in close contact with owners, especially not sleeping with children.

(iii) Further precautions
Fipronil can damage organisms living in the water. Dogs should not swim in watercours for 2 days after treatment. The alcoholic carrier may affect painted, lacquered or other surfaces or furniture in the apartment. This veterinary medicinal product is flammable. Hold away from heat, sparks, open flames and other sources of ignition.

Side effects:
After licking of the veterinary medicinal product, temporary saliva flow can occur, mainly caused by the properties of the carriers.
Side effects are extremely rarely to be expected; After the application, temporary skin reactions were at the application site (Skin discoloration, local alopecia, pruritus, erythema) as well as generalized itching or hair loss. In exceptional cases, saliva, reversible neurological symptoms (hypersensitivity, depression, nervous symptoms), Vomiting and respiratory symptoms observed. Overdoses are to be avoided.

Application during pregnancy and lactation:
Laboratory studies with Fpronil showed no evidence of teratogenic or fetotoxic effects. No studies were conducted to assess the safety of this veterinary medicinal product for pregnant or lactating animals. Therefore, during pregnancy and lactation, it should be used only after appropriate benefit-risk analysis by the attending veterinarian.

Interactions with other means:
Not known.

Dosage instructions with type and duration of the application:
Type of application:
For dripping on the skin. Only for external use. Depending on the weight of the animal, apply the veterinary medicinal product directly to the skin.

Dosage:
1 pipette (0.67 ml) for a dog with a body weight of 2 up to 10 kg, corresponding to a minimum recommended dose of 6.7 Mg / kg of Fipronil.
Keep the pipette upright. Clack the neck of the pipette slightly, so that the liquid collects completely in the main part of the pipette. Cross the pipette at the perforated spot. The fur between the shoulder blades tip until the skin is visible. Place the tip of the pipette on the skin and carefully empty the content on one or two places on the skin. Remove the pipette by scissors from the foil pillow or
1. Fold along the diagonal line to expose notch.
2. Disconnect the slide on the notch
3. Turn to open.
4. Drain fur vertices / content on the skin.

It is important to ensure that the veterinary medicinal product is applied to a location that can not lick the animal, and ensure that treated animals can not be mutually disclosed.
The coat should not be overly rolled over with the veterinary medicinal product, as it appears sticky at the treatment site. However, if this occurs, the coat will be within 48 Hours after administration look normal again.
For optimal control of an infestation with fleas or ticks, the treatment program of the local epidemiological situation can be adapted.
Since no corresponding verthe minimum distance of two treatments should be 4 weeks should be the minimum distance.

Overdose:
There were no side effects in target animal compatibility studies 8 weeks old puppies, observed in growth dogs and dogs with a weight of about 2 kg, which were treated three times with a dose that corresponded to the five times recommended dose. For overdose, the risk of side effects (See section 4.6) however. Therefore, animals should always be treated with the right pipette size tailored to the body weight.

Waiting period:
Not applicable.

Incompatibilities:
Not known.

Special warehouse and storage notes:
For this veterinary medicinal product, no special storage conditions are required with respect to temperature. Keep in original container to protect the content from light and moisture.

Type and texture of the container:
0.67 ml pipette, made of a 3-layer film: Polypropylene / COC / polypropylene, a solvent-free, laminated lacquer layer and a polyethylene / EVOH / polyethylene coupling. The pipettes are sealed in a child-safe 4-layer foil pillow consisting of LDPE / nylon / aluminum foil / polyester film and packed in an outer box. Pipettes with 0.67 each ML, 1.34 ml, 2.68 ml, 4.02 ml solution. There may not be all pack sizes on the market.

Prescription status:
Pharmacy

Admission holder:
Norbrook Laboratories Limited,
Station Works,
11 Camlough Road,
BT35 6JP Newry,
Co. Down, United Kingdom.

Distributor:
Bayer Vital GmbH,
51368 Leverkusen.

This leaflet was last revised in: 01/2017.

Source: Information of the leaflet
Status: 04/2017